elective Reinforcement Learning Deficits in chizophrenia Support Predictions from omputational Models of Striatal-Cortical Dysfunction

ethods: We administered two versions of a probabilistic selection task to 40 schizophrenia patients and 31 control subjects, using difficult o verbalize stimuli (experiment 1) and nameable objects (experiment 2). In an acquisition phase, participants learned to choose between hree different stimulus pairs (AB, CD, EF) presented in random order, based on probabilistic feedback (80%, 70%, 60%). We used analyses of ariance (ANOVAs) to assess the effects of group and reinforcement probability on two measures of contingency learning. To characterize he preference of subjects for choosing the most rewarded stimulus and avoiding the most punished stimulus, we subsequently tested articipants with novel pairs of stimuli involving either A or B, providing no feedback.